We connected Claude to our Statlas database and analyzed $1.5 billion in Meta spend across 320 accounts and $100 million in Google spend across 134 stores. The question: do platform bid controls actually deliver what they promise? Tony Chopp, CTC’s VP of Media Investment, walks through what we found — and what it means for…
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A CISO who sees a low CVE count and deprioritizes prompt injection is reading the scoreboard wrong. Prompt injection has held the No. 1 spot on the OWASP Top 10 for LLM Applications for three consecutive years. When two leaders of that list checked it against 6,639 labeled real-world incidents, it came back at No….
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Perplexity is launching Portable Computer today, a version of its agentic “Computer” platform that runs entirely on hardware users already own — starting with Nvidia’s DGX Spark desktop supercomputer and Linux machines equipped with Nvidia RTX GPUs. The launch, developed in close partnership with Nvidia, is one of the most aggressive attempts yet to move…
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Dave speaks to Michael Shackelford from Genrupt, to discuss the newest AI video model from ByteDance. They dive into Seedance 2.5, how they compare against other AI models, and how small businesses can create high-quality videos efficiently. They dive into the best practices for e-commerce businesses, the several ways users can leverage Seedance 2.5 and…
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Giulia Miotti is Senior Ecommerce Experience and Performance Manager at Bang & Olufsen, the Danish luxury audio brand where Scandinavian design meets high-fidelity sound. With over a decade of international experience across Adidas, Escada, and B&O, she’s built her career at the intersection of digital innovation and brand storytelling; leading content, SEO and AI search,…
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Anthropic is making a calculated bet that the biggest bottleneck in enterprise AI isn’t model intelligence — it’s the fact that most people still use AI alone. In an exclusive interview with VentureBeat, Scott White, Anthropic’s head of product for enterprise, laid out the company’s thesis for what it calls “multiplayer AI“: a shift away…
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https://directtoconsumer.typeform.com/DTC-Brand?utm_source=podcast-640&utm_medium=podcast To Subscribe to DTC Newsletter – https://dtcnews.link/signup Hannah Fleming runs performance marketing at Carve Designs (carvedesigns.com), the Northern California swim and apparel brand founded in 2003 and acquired by Komar Brands in December 2025. Before Carve she spent years at Amer Sports on the digital team behind Salomon, Atomic, Suunto, Arc’teryx and Wilson. If…
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IBM is announcing today at the annual Hot Chips conference what may be the most consequential change to mainframe architecture in decades: a processor whose cores can natively execute both IBM’s own instruction set and Arm’s — switching between the two in nanoseconds. The chip, which will power the next generation of IBM Z and…
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Building skincare from regenerative medicine — that’s the magic ✨
On The Kara Goldin Show, I sit down with Keith O’Briant, CEO of HYDRINITY Accelerated Skin Science — one of the fastest-growing professional skincare brands in the U.S.
We talk about how HYDRINITY began not as a traditional beauty brand, but as a regenerative medicine company developing advanced wound care products and drug delivery systems for oncology and hematology patients. Keith shares how that medical and scientific foundation evolved into a professional skincare brand built around patented injectable-grade hyaluronic acid, proprietary delivery systems, and regenerative technologies designed to support skin health and deliver visible results.
We also get into what “science-backed skincare” really means, why delivery systems matter as much as ingredients, and how consumers can better understand the difference between marketing claims and clinically backed innovation. Keith also shares what he learned from more than 30 years in life sciences, including leadership roles at Pfizer and Shire, and what it has taken to scale HYDRINITY into more than 4,000 professional practices in the U.S. and more than 40 countries globally since launching in 2022.
If you’re interested in learning how regenerative medicine is shaping the future of skincare, what it takes to build a science-first brand in a crowded beauty market, or why professional skincare is entering a whole new chapter — check out the interview on my podcast. You can find it here or anywhere you listen to podcasts 🎧
Are you interested in sponsoring and advertising on The Kara Goldin Show, which is now in the Top 1% of Entrepreneur podcasts in the world? Let me know by contacting me at karagoldin@gmail.com. You can also find me @KaraGoldin on all networks.
To learn more about Keith O’Briant and HYDRINITY:
https://www.hydrinity.com/
https://www.instagram.com/hydrinity/
https://www.tiktok.com/@hydrinity
https://www.linkedin.com/company/hydrinity/
https://www.linkedin.com/in/keith-o-briant/
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Check out our website to view this episode’s show notes: https://karagoldin.com/podcast/882
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FOLLOW UP WITH ANDREW X: https://x.com/andrewjfaris Email: podcast@ajfgrowth.com Work With AJF Growth: https://ajfgrowth.com 00:00 Intro: Understanding Returning Customer Ad Spend03:29 Why Retention Ad Spend Can Drive Incremental Revenue08:17 Which Brands Should Spend on Retention?10:36 Product Releases & Retention Advertising13:08 How to Measure Returning Customer Spend14:14 Combining New & Existing Customer Spend16:27 Which Brands Should NOT…
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