In this episode, we’re breaking down how to apply “Doge-like” principles to improve your business practices and boost your productivity. The economic climate is shifting and now’s the time to trim back the fat.
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Are you frustrated by unpredictable ROAS and rising Facebook ad costs that make scaling your Shopify brand feel impossible? You’re definitely not alone. Many brands see their first customer acquisition barely break even—or even lose money—forcing them to rely on retention just to stay afloat. In this episode, I’m joined by Manel Gomez, CEO and…
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On this episode of The Kara Goldin Show, we’re joined by Chris Moxham, CEO of Transcripta Bio, a biotech company revolutionizing drug discovery through the power of AI and transcriptomics. With a unique platform built on a vast perturbation atlas of small molecules, Transcripta is uncovering novel opportunities across a wide range of human diseases—faster and with more precision than traditional methods.
In our conversation, Chris shares the story behind Transcripta Bio and how the team is building frontier AI models to predict biological responses from potential drug compounds. We dive into what makes their approach different, why a transcriptome-first strategy matters, and how they’re unlocking insights that have the potential to lead to more targeted and effective therapies. Chris also speaks about the mindset required to lead in a rapidly evolving industry, the collaboration between AI and human expertise, and what’s next for the company.
If you’re curious about the intersection of science and technology, the future of drug discovery, or the kind of leadership it takes to build something truly transformative, this episode is one you won’t want to miss. Now on The Kara Goldin Show.
Are you interested in sponsoring and advertising on The Kara Goldin Show, which is now in the Top 1% of Entrepreneur podcasts in the world? Let me know by contacting me at [email protected]. You can also find me @KaraGoldin on all networks.
To learn more about Chris Moxham and Transcripta Bio:
https://www.transcriptabio.com
https://www.linkedin.com/in/christophermoxham
https://www.instagram.com/transcriptabio
https://www.linkedin.com/company/transcriptabio
Sponsored By:
Shopify – Sign up for your one-dollar-per-month trial period at Shopify.com/kara
RULA – Go to Rula.com/KARAGOLDIN for convenient therapy that’s covered by insurance.
Range Rover Sport – The Range Rover Sport is your perfect ride. Visit LandRoverUSA.com and check it out.
Check out our website to view this episode’s show notes: https://karagoldin.com/podcast/676
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Tariffs are here—and they’re not hitting every brand the same. In this solo episode, Taylor walks through a critical 4 part framework designed to help ecommerce founders and operators craft the right response based on their unique balance sheet realities. Whether you’re cash rich with deep inventory or strapped for both, this episode will help…
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Mike Jackness and Aymeric catch up on their e-commerce journey as friends and talk about how timing and luck are so important in entrepreneurial success. Success is always a mix of luck, tenacity, and grit. It takes a bit of luck to be in the…
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On this episode of Honest Ecommerce, we have Demi Marchese, Founder and Head of Brand at 12th Tribe.
We talk about how she scaled brand voice using AI, built systems to support sustainable growth, stayed focused through trend overload, and empowered her team to drive toward a 9-figure business and so much more!
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On this episode of The Kara Goldin Show, I’m joined by Simone Kendle, CEO of Wove, the custom jewelry brand changing the way people experience luxury. With a mission to bring personalization and storytelling to the forefront of fine jewelry, Wove is helping customers design one-of-a-kind pieces that truly mean something.
Simone shares her journey to leading Wove, what sets the brand apart in a traditional industry, and how she’s scaling a modern company rooted in authenticity, innovation, and purpose. We also talk about what it takes to grow fast, stay mission-aligned, and connect deeply with today’s consumers.
If you’re curious about building a standout brand, redefining luxury, or leading with intention—this one’s for you. Now on The Kara Goldin Show.
Are you interested in sponsoring and advertising on The Kara Goldin Show, which is now in the Top 1% of Entrepreneur podcasts in the world? Let me know by contacting me at [email protected]. You can also find me @KaraGoldin on all networks.
To learn more about Simone Kendle and Wove:
https://www.instagram.com/simonekendle/
https://www.linkedin.com/in/simone-kendle/
https://www.instagram.com/wove_made/
https://www.linkedin.com/in/simon
https://www.wovemade.com/
Sponsored By:
Open Phone – OpenPhone is offering 20% off your first 6 months! Just go to OpenPhone.com/KaraGoldin
Range Rover Sport – The Range Rover Sport is your perfect ride. Visit LandRoverUSA.com and check it out.
ACORNS. Head to acorns.com/KARA or download the Acorns app to start saving and investing for your future today!
Check out our website to view this episode’s show notes: https://karagoldin.com/podcast/675
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On this week’s episode of the Modern Retail Podcast, the staff is going deep into modern marketing strategies. First up, executive editor Anna Hensel and senior reporter Gabriela Barkho talk about what was top of mind for executives at the Modern Retail Marketing Summit. Tariffs — and how to respond to them — were a…
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Josh Durham launched Aligned Growth Management, an influencer marketing agency, in 2020. He says the influencer industry has evolved from the halcyon days a decade ago when affiliate-based creators could generate 5x returns. Influencer marketing circa 2025, according to Josh, is a long-term play. Success depends on quality products, engaged creator audiences, and content that…
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